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Image Search Results
Journal: Amyotrophic lateral sclerosis & frontotemporal degeneration
Article Title: Combination of ciprofloxacin/celecoxib as a novel therapeutic strategy for ALS.
doi: 10.1080/21678421.2022.2119868
Figure Lengend Snippet: Figure 3. ALS-pathology related NDE biomarker levels in ALS vs. control samples. Wilcox test comparing neural-derived blood exosomal biomarkers: TDP-43 (A) and LC3 (B) between patients with ALS and healthy volunteers (N ¼ 35 for ALS and 25 for control per group) as obtained in a baseline study.
Article Snippet: LC3 and TDP-43 were quantitatively measured in the NDE protein extracts using
Techniques: Biomarker Discovery, Control, Derivative Assay
Journal: Amyotrophic lateral sclerosis & frontotemporal degeneration
Article Title: Combination of ciprofloxacin/celecoxib as a novel therapeutic strategy for ALS.
doi: 10.1080/21678421.2022.2119868
Figure Lengend Snippet: Figure 4. ALS-pathology related biomarker levels in PrimeC treated ALS patients over time. (A,B) Average ALS-pathology related serum NDE marker levels over time (pre in red, interim in light blue, and end of study in dark blue). (A) TDP-43 levels. (B) LC3 levels. (C,D) Average serum NFL (C) and pNFH (D) over time (pre in red, interim in light blue, and end of study in dark blue). P values tests whether the means at pre-treat are similar compared to the mean at end-of-treat, based on a mixed model for repeated measures.
Article Snippet: LC3 and TDP-43 were quantitatively measured in the NDE protein extracts using
Techniques: Biomarker Discovery, Marker